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LansoprazoleSystematic (IUPAC) name2-(methylsulfinyl)-1H-benzoimidazoleIdentifiersCAS number103577-45-3ATC codeA02BC03PubChem3883DrugBankAPRD00077ChemSpider3746Chemical dataFormulaC16H14F3N3O2S Mol. mass369.363 g/molSMILESeMolecules & PubChemPharmacokinetic dataBioavailability80% or moreProtein binding97%MetabolismHepatic (CYP3A4- and CYP2C19-mediated)Half life1–1.5 hoursExcretionRenal and fecalTherapeutic considerationsLicence dataUS FDA:linkPregnancy cat.B3(AU) B(US)Legal status℞ Prescription onlyRoutesOral, IVLansoprazole (lan-SOE-pra-zole, INN) is a proton pump inhibitor which prevents the stomach from producing acid. It is manufactured by a number of companies worldwide under several brand names (some brand names include: Prevacid, Helicid, Zoton, Inhibitol). It was first approved by the FDA in 1995.// PharmacologyLansoprazole is a proton pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPI's available.Lansoprazole's plasma elimination half-life is not proportional to the duration of the drug's effects (i.e. gastric acid suppression). The mean plasma elimination half-life is 1.5 hours, and the effects of the drug last for over 24 hours after it has been used for 1 day or more. IndicationsLansoprazole is indicated for:Treatment of ulcers of the stomach and duodenum, and NSAID-induced ulcersTreatment of gastroesophageal reflux disease (GERD) (also known as acid reflux disease)Treatment of Zollinger-Ellison SyndromeAdjunctive treatment of Helicobacter pylori infection, alongside antibiotics Drug InteractionsPPI’s reduce absorption of antifungals (itraconazole and ketoconazole) and possibly increase Digoxin in plasmaIncreases plasma concentrations of Cilostazol (risk of toxicity)Absorption of lansoprazole possibly reduced by:sucralfateampicillinbisacodyldelavirdinefluvoxamineiron saltstheophyllinevoriconazoleaminophylline and theophyllineastemizole Side effectsInfrequent: dry mouth, insomnia, drowsiness, blurred vision, rash, pruritusRarely and very rarely: taste disturbance, liver dysfunction, peripheral oedema, hypersensitivity reactions (including bronchospasm, urinary, angioedema, anaphylaxis), photosensitivity, fever, sweating, depression, interstitial nephritis, blood disorders (including leukopenia, leukocytosis, pancytopenia, thrombocytopenia), arthralgia, myalgia, skin reactions (including Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous eruption)Severe: Gastro-intestinal disturbances (such as nausea 1.3%, abdominal pain 2.1%, diarrhea 3.8%). Brand namesThe drug is sold under several brand names, including: Agopton (Germany)Aprazol (Turkey)Duogast (Syria)Lanpro (India)Lanzol (India)Lansox (Italy)Lanton (Israel)Lanzor (France)Laprazol (Greece)Limpidex (Italy)Monolitum (Spain)Ogast and OgastORO (France)Prevacid (U.S. and Canada) Prevacid is a product of TAP Pharmaceutical Products.Prosogan and Prosogan FD (Indonesia)Refluxon (Hungary)SOLOX (New Zealand)Takepron (Japan)Zoton (Italy, Ireland, Australia, UK)ZOMEL (Ireland)Lansoprazole is also available as a generic drug in the UK, Belgium, France, Colombia, Italy and Mexico.
For hyperacidity problems, doctors prescribe Prevacid (Lansoprazole) to reduce high levels of acidity in the stomach.CHICAGO, Illinois (AP) -- Taking such popular heartburn drugs as Nexium, Prevacid or Prilosec for a year or more can raise the risk of a broken hip markedly in people over 50, a large study in Britain found. And when "proton pump inhibitor" Can prednisone cause hair loss, calcium coral gold, canine effects lasix, car brite mobile detailing, calcium carbonate in acid, calcium carbonate photo, canadian pharmacies norvasc, can prevacid cause sleepinessEuflexxa Lipitor Actonel Fosamax Effexor Protonix Plavix Celebrex Flomax Nexium Synvisc Prevacid Evista Juvederm Orthovisc Restylane Zyprexa HyalganMillions of Americans suffering from heartburn and acid reflux takea class of prescription drugs that includes Nexium, Prevacid andothers. Nexium, Prevacid can hold up the bodies ability to use calcium. With 180 million prescriptions a year and sales topping $14billion, these drugs are a success story. It is used in short-term treatments of hyperacidity-related diseases.. PPIs are a class of drugs that include Aciphex, Nexium, Prevacid, Prilosec, and ProtonixThe study shows a link between long-term use of proton pump inhibitors and greater likelihood of osteoporosis-related fractures of the hip or spine. However you can cure this illness
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Prevacid presents several treatment options for heartburn associated with acid reflux disease as well as reducing the risk of NSAID-related stomach ulcers from coming back.
Treatments for Acid Reflux, Heartburn and Stomach Ulcers- Prevacid
Experiencing abdominal pain? You might be suffering from an ulcer. The two most common types of ulcers are duodenal and stomach ulcers. Find out more about ulcer symptoms.
Stomach Ulcers & Duodenal Ulcer Information- Prevacid
Learn about the prescription medication Prevacid (Lansoprazole), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.
Prevacid (Lansoprazole) Drug Information: Uses, Side Effects, Drug ...
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Find information about the drug Prevacid in the Walgreens.com Health Library.
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