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VardenafilSystematic (IUPAC) name4--9-methyl-7-propyl- 3,5,6,8-tetrazabicyclonona-3,7,9-trien-2-oneIdentifiersCAS number224785-90-4ATC codeG04BE09PubChem110634DrugBankAPRD00699ChemSpider99300Chemical dataFormulaC23H32N6O4S Mol. mass488.604 g/molPharmacokinetic dataBioavailability15%Protein binding95%MetabolismHepatic (CYP3A4)Half life4–5 hoursExcretionBiliaryTherapeutic considerationsPregnancy cat.B3 (Au), B (U.S.)Legal statusPrescription Only (S4)(AU) POM(UK) ℞-only(US)RoutesOralVardenafil (INN) is a PDE5 inhibitor used for treating impotence (erectile dysfunction) that is sold under the trade name Levitra (Bayer AG), (GSK), (SP) .// HistoryVardenafil was co-marketed by Bayer Pharmaceuticals,GSK, and SP under the trade name Levitra. As of 2005, the co-promotion rights of GSK on Levitra have been returned to Bayer in many markets outside the U.S. In Italy, Bayer sells vardenafil as Levitra and GSK sells it as Vivanza, thus, because of European Union trade rules, parallel imports might result in Vivanza sold next to Levitra in the E.U. Clinical useMain article: PDE5 inhibitorVardenafil's indications and contra-indications are the same as with other PDE5 inhibitor; it is closely related in function to sildenafil (Viagra) and tadalafil (Cialis). Structurally, the difference between a vardenafil molecule and the others is a methyl group and a nitrogen atom's position. Vardenafil's relatively short effective time is comparable to sildenafil's. Adverse drug reactionsThe common, adverse drug reactions (side effects) are the same as with other PDE5 inhibitors. The frequent vardenafil-specific side effect is nausea; the infrequent side effects are: abdominal pain, back pain, photosensitivity, abnormal vision, eye pain, facial oedema, hypertension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism. (Rossi, 2004)One possibly serious, but rare, side effect with vardenafil is heart attack. Also in rare cases, vardenafil use may damage penile tissue, resulting in permanent impotence. Health Canada (2006) (Citation needed.)On 18 October 2007, the FDA announced that a warning about possible deafness (sudden hearing loss) would be added to the drug labels of Vardenafil, and other PDE5 inhibitors. Drug interactionsVardenafil should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure). Dose formsIt is available in 2.5 mg, 5 mg, 10 mg, and 20 mg doses in round orange tablets. The normal starting dose is 10 mg (roughly equivalent to 50 mg of sildenafil). Vardenafil should be taken 1 to 2 hours prior to sexual activity, with a maximum dose frequency of once per day. In some territories, such as the UK, only certain doses may be available, i.e. 5 mg, 10 mg, and 20 mg. See alsoPDE5 inhibitorSildenafil (Viagra)Tadalafil (Cialis) Notes^ "FDA Announces Revisions to Labels for Cialis, Levitra and Viagra". Food and Drug Administration. 2007-10-18. http://www.fda.gov/bbs/topics/NEWS/2007/NEW01730.html. Retrieved on 2007-12-08.
.THis blog about Erectile dysfunction..harmacokinetics drug Levitra: Suction drug Levitra.Sex is an important element of physical satisfaction for both men and women.comModern lovers seem to be equally fervent about being great in bed! According to a healthcare information company, Wolters Kluwer, in 2005, Americans spent about $1.Marital relationship involves adjustment, compromise, trust and understanding with your partner.Levitra is an oral prescription medication used in the treatment of erectile dysfunction or impotence in men.News and articlesKamagra Rx Obsessed For Quality Erectile Dysfunction (ED) Pills kamagra, Fast kamagra oral jellies, Generic Viagra, Caverta, Zenegra, Generic Cialis, Forzest, Generic Levitra etc..Many men experience improvement in erectile function after taking Viagra, Levitra, or Cialis. Still levitra stands one step ahead of cialis.They are not the popular Viagra or Levitra.Back fetching levitra selling convey your MD glareOne of the best websites where you can order Viagra, Kamagra, Cialis, Levitra, Lovegra cheap, fast and 100% real!casodex black box warning,cheap levitra tablets,celexa withdrawals,canine dosage zantacbobs barefoot coral calcium,buy propecia on the net,breast enhancement dothan,buy prescription levitraa great resource on Levitra. KwikMed is your online pharmacy.Cialis (Tadalafil) de Lilly ICOS está aprobado por la FDA el tratamiento oral para los hombres que tienen dificultad para lograr o mantener la erección para el
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