flonase
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flonase
FluticasoneSystematic (IUPAC) nameS-(fluoromethyl) (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopentaphenanthrene-17-carbothioateIdentifiersCAS number80474-14-2ATC codeD07AC17 & D07AC04 (topical)R01AD08 (nasal)R03BA05 (inhaled)R01AD12 (furoate)PubChem5311101DrugBankAPRD00065ChemSpider4470631Chemical dataFormulaC22H27F3O4S Mol. mass444.508 g/molSMILESeMolecules & PubChemPharmacokinetic dataBioavailability0.51% (Intranasal)Protein binding91%MetabolismIntranasalHepatic (CYP3A4-mediated)Half life10 hoursExcretionRenalTherapeutic considerationsPregnancy cat.C for Intranasal and InhaledLegal statusPOM(UK) ℞-only(US)RoutesIntranasal, Inhaled, Topical Cream or OintmentFluticasone is a synthetic corticosteroid.Both the furoate and propionate forms are used as topical anti-inflammatories:Fluticasone propionateFluticasone furoate See alsoFluticasone furoateFluticasone propionateAnti-inflammatory uses of glucocorticoidsv • d • eDecongestants and other nasal preparations (R01)TopicalSympathomimetics, plainCyclopentamine • Ephedrine • Phenylephrine • Oxymetazoline • Tetryzoline • Xylometazoline • Naphazoline • Tramazoline • Metizoline • Tuaminoheptane • Fenoxazoline • Tymazoline • EpinephrineAntiallergic agents,excluding corticosteroidsSpaglumic acidhistamine antagonists (Levocabastine, Antazoline, Thonzylamine)mast cell stabilizer (some are also antihistamines) (Cromoglicic acid, Nedocromil, Azelastine, Olopatadine)CorticosteroidsBeclometasone • Prednisolone • Dexamethasone • Flunisolide • Budesonide • Betamethasone • Tixocortol • Fluticasone • Mometasone furoate • Triamcinolone • CiclesonideOther nasal preparationsCalcium hexamine thiocyanate • Retinol • Ipratropium bromide • Ritiometan • Mupirocin • Hexamidine • Framycetin • Hyaluronic acidSystemic use:SympathomimeticsPhenylpropanolamine • Pseudoephedrine • Phenylephrine • Phenylpropylaminev • d • eDrugs for obstructive airway diseases: asthma/COPD (R03)Adrenergics, inhalantsShort acting β2-agonistsSalbutamol/Levosalbutamol • Fenoterol • Terbutaline • Pirbuterol • Procaterol • Bitolterol • Rimiterol • Carbuterol • Tulobuterol • ReproterolLong acting β2-agonists (LABA)Arformoterol • Bambuterol • Clenbuterol • Formoterol • Salmeterol Ultra LABA: IndacaterolotherEpinephrine • Hexoprenaline • Isoprenaline (Isoproterenol) • Orciprenaline (Metaproterenol)GlucocorticoidsBeclometasone • Budesonide • Ciclesonide • Fluticasone • MometasoneAnticholinergics/muscarinic antagonistIpratropium • TiotropiumMast cell stabilizersCromoglicate • NedocromilXanthinesDoxofylline • Theobromine • Theophylline/AminophyllineEicosanoid inhibitionLeukotriene antagonistsMontelukast • Pranlukast • ZafirlukastLipoxygenase inhibitorZileutonThromboxane receptor antagonistsRamatroban • SeratrodastCombination productsBudesonide/formoterol • Fluticasone/salmeterol • Ipratropium/salbutamolv • d • eCorticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) (Endogenous in CAPS)MineralocorticoidsALDOSTERONE · DESOXYCORTONE · Deoxycorticosterone · FludrocortisoneGlucocorticoidsCORTISONE · HYDROCORTISONE/CORTISOL · Beclometasone · Betamethasone · Budesonide · Ciclesonide · Cloprednol · Cortivazol · Deflazacort · Dexamethasone · Fluticasone · Flunisolide · Hydrocortisone aceponate · Hydrocortisone buteprate · Hydrocortisone butyrate · Meprednisone · Methylprednisolone · Methylprednisolone aceponate · Mometasone furoate · Paramethasone · Prednicarbate · Prednisolone · Prednisone · Prednylidene · Rimexolone · TriamcinoloneOther/ungroupedcorticosteroidsAlclometasone · Amcinonide · Clobetasol · Clobetasone · Clocortolone · Desonide · Desoximetasone · Diflorasone · Diflucortolone · Difluprednate · Fluclorolone · Fludroxycortide · Flumetasone · Fluocinolone acetonide · Fluocinonide · Fluocortin · Fluocortolone · Fluorometholone · Fluperolone · Fluprednidene · Formocortal · Halcinonide · Halometasone · Loteprednol · Medrysone · Tixocortol · UlobetasolAldosterone antagonistsSpironolactone · Eplerenone · Potassium canrenoate · CanrenoneSynthesisTrilostane · Carbenoxolone · Aminoglutethimide · Metyrapone
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Even more about flonase
flonase
Relieve nasal symptoms from indoor and outdoor allergies.
FLONASE relieves indoor and outdoor nasal allergy symptoms
FLONASE treatment options for outdoor symptoms of nasal allergies and other nasal allergies.
About FLONASE nasal spray - treat symptoms of outdoor nasal outdoor ...
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On our site you have search description of pills ... Drugs name: Flonase(Fluticasone) Fluticasone propionate, the active component of Flonase Nasal Spray, is a synthetic ...
Pills description
Flonase. From $41.98 per pill. Flonase is used for treatment of allergic and non-allergic nasal symptoms including congestion, sneezing, itching, and runny nose.
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