Zebeta
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Zebeta
BisoprololSystematic (IUPAC) name1-phenoxy]-3-(1-methylethylamino)propan-2-olIdentifiersCAS number66722-44-9ATC codeC07AB07PubChem2405DrugBankAPRD00257ChemSpider2312Chemical dataFormulaC18H31NO4 Mol. mass325.443 g/molPharmacokinetic dataBioavailability>90%Protein binding30%Metabolism50% HepaticHalf life10-12hoursExcretion ?Therapeutic considerationsLicence dataUSPregnancy cat.C(AU) C(US)Legal status℞ Prescription onlyRoutesoralBisoprolol is a drug belonging to the group of beta blockers, a class of drugs used primarily in cardiovascular diseases. More specifically, it is a selective type β1 adrenergic receptor blocker.// Pharmacology and biochemistry β1 SelectivityBisoprolol has a higher degree of β1-selectivity compared to other β1-selective β-blockers such as atenolol, metoprolol and betaxolol. However Nebivolol is approximately 3.5 times more β1-selective. Antihypertensive effectBisoprolol has a stronger antihypertensive effect than propranolol. CardioprotectionBisoprolol in animal models has been shown to be cardioprotective. Renin-angiotensin systemBisoprolol inhibits renin secretion by about 65% and tachycardia by about 35%. Pharmacology of side-effectsIn animal testing bisoprolol compared to propranolol has shown less sedative effects and only slightly reduced glucose tolerance. IndicationsBisoprolol (Concor, Zebeta, Concore, Monocor) can be used to treat cardiovascular diseases such as hypertension, coronary heart disease, arrhythmias, ischemic heart diseases and treatment of myocardial infarction after the acute event. Patients with compensated congestive heart failure may be treated with Bisoprolol as a comedication (usually together with an ACE inhibitor, a diuretic and a digitalis-glycosid, if indicated). In patients with congestive heart failure, it reduces the need for and the consumption of oxygen of the heart muscle. It is very important to start with low doses, as bisoprolol reduces also the muscular power of the heart, which is an undesired effect in congestive heart failure.The drug is also used to treat other conditions, including dysautonomia, anxiety and hyperthyroidism (over active thyroid gland).Bisoprolol will give a positive result in doping tests.
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Zebeta
Learn about Zebeta including potential side effects and drug interactions. ... Why is Zebeta prescribed? Zebeta, a type of medication known as a beta-blocker, is used to treat high ...
Zebeta Drug Information and Side Effects on HealthSquare.com
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Zebeta manufacturer - Canadian Pharmacy Online™
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Revolution Health ... What is Zebeta (Bisoprolol)? Bisoprolol is in a group of drugs called beta-blockers.
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